Antihypertensive Use and the Risk of Alzheimer's Disease and Related Dementias among Older Adults in the USA.

Xi PanDonglan ZhangJi Haeng HeoChanhyun ParkGang LiChristine M Dengler-CrishYan LiYian GuHenry N YoungDevin L LavenderLu Shi

Published in: Drugs & aging (2022)

Findings of the study suggest the need for evidence-based drug therapy to manage hypertension in later adulthood and warrant further investigation into the mechanism underlying the protective effect of antihypertensives, particularly ACEIs, against the development of AD among older adults with hypertension.

Keyphrases

blood pressure
hypertensive patients
depressive symptoms
early life
mesenchymal stem cells
bone marrow
arterial hypertension
adverse drug
smoking cessation