Distinctive clinical and genetic features of lean vs overweight fatty liver disease using the UK Biobank.

Daljeet ChahalDivya SharmaSareh KeshavarziFakhar Ali Qazi ArisarKeyur PatelWei XuMamatha Bhat

Published in: Hepatology international (2022)

Our analysis suggests that lean and overweight or obese NAFLD are distinct entities. We have developed a risk score incorporating both clinical and genetic factors that accurately classify lean patients with NAFLD, with the potential to serve as a tool for screening purposes.

Keyphrases

weight loss
bone mineral density
physical activity
genome wide
weight gain
adipose tissue
type diabetes
metabolic syndrome
bariatric surgery
copy number
gene expression
risk assessment
obese patients