Comparative Study of DNA ploidy and BRAF Immunohistochemistry between Colonic Adenocarcinoma and Inflammatory Colonic Lesions.
Heba Khalil Mohamed KhalilOlfat Ali HammamShady Elia AnisMohamed Abd El-Hady ElashryChetana Prakash DeshmukhPublished in: Asian Pacific journal of cancer prevention : APJCP (2023)
Based on significant difference in ploidy between adenocarcinoma and UC and between SPF and ploidy, assessment of ploidy by DNA cytometry for UC and other colitis could therefore predict impending malignant transformation before development of colonic dysplasia. Also measuring SPF in adenocarcinoma helps to select patients who could greatly benefit from chemotherapy. DL has vital role in staging GI cancers.