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Brain Homogenate of a Rat Model of Alzheimer's Disease Modifies the Secretome of 3D Cultured Periodontal Ligament Stem Cells: A Potential Neuroregenerative Therapy.

Fariba MohebichamkhoramiZahra NiknamMona KhoramjouyElmira HeidarliRasoul GhasemiSimzar HosseinzadehSeyedeh Sarvenaz MohseniArman Hajikarim-HamedaniAmirhossein HeidariYekta GhaneMatin MahmoudifardHakimeh ZaliMehrdad Faizi
Published in: Iranian journal of pharmaceutical research : IJPR (2022)
The modified secretome derived from 3D cultured spheroids of PDLSCs treated by BH-AD as a reservoir of regenerating neural factors can serve as a potential source for AD treatment.
Keyphrases
  • stem cells
  • endothelial cells
  • human health
  • white matter
  • cognitive decline
  • cell therapy
  • multiple sclerosis
  • risk assessment
  • mesenchymal stem cells
  • newly diagnosed
  • replacement therapy
  • smoking cessation