Data-based RNA-seq simulations by binomial thinning.

Published in: BMC bioinformatics (2020)

Using data simulated from a theoretical model can substantially impact the results of a study. We developed more realistic simulation techniques for RNA-seq data. Our tools are available in the seqgendiff R package on the Comprehensive R Archive Network: https://cran.r-project.org/package=seqgendiff.

Keyphrases

rna seq
single cell
electronic health record
big data
quality improvement
machine learning
virtual reality