The impact of histological variants on outcomes after open radical cystectomy for muscle-invasive urothelial bladder cancer: results from a single tertiary referral centre.

Richard NasproMarco FinatiMarco RoscignoFederico PellucchiGiovanni La CroceMario SodanoMichele ManicaDaniela ChinagliaLuigi F Da Pozzo

Published in: World journal of urology (2020)

The presence of histological variants at radical cystectomy seems to be weakly associated with reduced survival compared to pure urothelial bladder cancer paired for pathologic stage. The association of histological variants with advanced and biologically aggressive tumours suggests the need for attention on the overall management of these patients, in particular for micropapillary, sarcomatoid and small cell differentiation.

Keyphrases

copy number
end stage renal disease
high grade
newly diagnosed
chronic kidney disease
skeletal muscle
urinary tract
primary care
minimally invasive
working memory
peritoneal dialysis
lymph node