Arrhythmogenic Cardiomyopathy: Definition, Classification and Arrhythmic Risk Stratification.
Marisa VarrentiGabriele FragassoAntonio FronteraMatteo BaroniLorenzo GigliSara VargiuGiulia ColomboMarco CarbonaroMarco PaolucciFederica GiordanoFabrizio GuarraciniPatrizio MazzonePublished in: Journal of clinical medicine (2024)
Arrhythmogenic cardiomyopathy (ACM) is a heart disease characterized by a fibrotic replacement of myocardial tissue and a consequent predisposition to ventricular arrhythmic events, especially in the young. Post-mortem studies and the subsequent diffusion of cardiac MRI have shown that left ventricular involvement in arrhythmogenic cardiomyopathy is common and often develops early. Regarding the arrhythmic risk stratification, the current scores underestimate the arrhythmic risk of patients with arrhythmogenic cardiomyopathy with left involvement. Indeed, the data on arrhythmic risk stratification in this group of patients are contradictory and not exhaustive, with the consequence of not correctly identifying patients at a high arrhythmic risk who deserve protection from arrhythmic death. We propose a literature review on arrhythmic risk stratification in patients with ACM and left involvement to identify the main features associated with an increased arrhythmic risk in this group of patients.
Keyphrases
- left ventricular
- heart failure
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ejection fraction
- peritoneal dialysis
- magnetic resonance imaging
- prognostic factors
- machine learning
- computed tomography
- pulmonary hypertension
- deep learning
- acute coronary syndrome
- left atrial
- percutaneous coronary intervention
- cardiac resynchronization therapy
- diffusion weighted imaging
- data analysis
- catheter ablation