Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung.

Aoi KurodaAhmed E HegabGao JingtaoShuji YamashitaNobuyuki HizawaTohru SakamotoHideyasu YamadaSatoshi SuzukiMakoto IshiiHo NamkoongTakanori AsakuraMari OzakiHiroyuki YasudaJunko HamamotoShizuko KagawaKenzo SoejimaTomoko Betsuyaku

Published in: Respiratory research (2017)

ALDH2 polymorphism has several subtle effects on the lungs, some of which are similar to changes observed during normal aging, suggesting a "premature lung aging" effect.

Keyphrases

endothelial cells
genome wide
induced pluripotent stem cells
copy number
gene expression
dna methylation
genome wide analysis