A Case Report and Literature Review of Pseudo-TORCH Syndrome Type 2 (PTORCH2).
Rami A MiskLama QawasmeFawzy M AbunejmaBahaa Ibrahim Abu RahmaEhab Mohammad AbuawwadRaja Imad Abu IramAbdulrahman Hussein KarakiTareq Z AlzughayyarJihad Samer ZalloumPublished in: Case reports in pediatrics (2022)
A pseudo-TORCH syndrome is a rare autosomal recessive disease characterized by intracranial calcification and microcephaly, leading to spasticity and seizures, but the serology of TORCH infection is negative. We present a 4-day-old female patient with jaundice, abnormal movement, and convulsions who was found to be homozygous for the missense USP18 gene mutation that causes pseudo-TORCH syndrome 2 (PTORCH2). The patient was managed with conservative measures.