Predictors of toxicity after curative reirradiation with intensity modulated radiotherapy or proton therapy for recurrent head and neck carcinoma: new dose constraints for pharyngeal constrictors muscles and oral cavity.

Arnaud BeddokXavier MaynadierSamar KrhiliCatherine Ala EddineLaurence ChampionAnne ChillesFarid GoudjilSofia ZefkiliMalika AmessisOlivier ChoussyChristophe Le TourneauIrene BuvatGilles CréhangeMatthieu CartonValentin Calugaru

Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2023)

Our analysis depicted an association between the dose to OAR and the risk of developing moderate to severe dysphagia and dysgeusia and proposed new dose constraints for PCM (36.7 Gy) and oral cavity (20.5 Gy).

Keyphrases

early stage
oxidative stress
radiation therapy
high intensity
squamous cell carcinoma
rectal cancer
drug induced
data analysis