Alterations in optical coherence tomography and optical coherence tomography angiography findings in children with partial biotinidase deficiency.

In the partial BD patients, the vascular density in the macula and optic disc region is decreased in childhood, when compared to the control group. In patients with partial BD, it would be very useful to detect the early neurovascular changes that may occur during the course of the disease by means of a noninvasive technique such as OCTA.