Mapping microarchitectural degeneration in the dilated ascending aorta with ex vivo diffusion tensor imaging.

Mofei WangJustin A Ching-JohnsonHao YinCaroline O'NeilAlex X LiMichael W A ChuRobert BarthaJ Geoffrey Pickering

Published in: European heart journal open (2023)

high-field DTI can detect ascending aorta medial degeneration and can differentiate TAAs in accordance with their histopathology, especially elastin and GAG changes. This non-destructive window into aortic medial microstructure raises prospects for probing the risks of TAAs beyond lumen dimensions.

Keyphrases

pulmonary artery
aortic dissection
white matter
coronary artery
aortic valve
pulmonary hypertension
pulmonary arterial hypertension
high resolution
human health
multiple sclerosis
current status
molecular dynamics simulations
ultrasound guided
high density
risk assessment
climate change
left ventricular