Impaired Cognitive Abilities in Siblings of Patients with Temporal Lobe Epilepsy.

Langzi TanYayu ChenWenyue WuChaorong LiuYujiao FuJialinzi HeMin ZhangGe WangKangrun WangHongyu LongWenbiao XiaoBo XiaoLili Long

Published in: Neuropsychiatric disease and treatment (2020)

Patients with TLE exhibit cognitive impairment. Executive function is worse in patients with left TLE than in those with right TLE. Siblings show impaired visuospatial function relative to controls. Thus, cognitive deficits in TLE patients have a genetic component and are independent of seizures or AED use.

Keyphrases

temporal lobe epilepsy
cognitive impairment
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
intellectual disability
prognostic factors
peritoneal dialysis
genome wide
gene expression
copy number
autism spectrum disorder
patient reported
dna methylation