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DNA methylation and aeroallergen sensitization: The chicken or the egg?

Anna KilanowskiSimon Kebede MeridSarina AbrishamcarDakotah FeilElisabeth ThieringMelanie WaldenbergerErik MelénAnnette PetersMarie StandlAnke Hüls
Published in: Clinical epigenetics (2022)
The results indicate that DNAm may be a cause or consequence of aeroallergen sensitization depending on genomic location. Allergy-related MRS, identified as a potential cause of sensitization, can be considered as a cross-sectional biomarker of disease. Differential DNAm in individual CpGs, identified as mediators of the development of sensitization, could be used as clinical predictors of disease development.
Keyphrases
  • dna methylation
  • genome wide
  • copy number
  • nk cells
  • risk assessment