Ex vivo evaluation of the influence of pH on the ophthalmic safety, antibacterial efficacy and storage stability of povidone-iodine.
Sachin S ThakurArian BaiDoris ChanJonathan LuMarie LuAimee SuJanesha PereraSimon SwiftDarren SvirskisIlva Dana RupenthalPublished in: Clinical & experimental optometry (2021)
Ophthalmic application of povidone-iodine can be optimised by adjusting the pH of the formulation to 7.0 using phosphate buffer, reducing irritancy while maintaining adequate antibacterial efficacy and storage stability.