Persistent post-COVID headache is associated with suppression of scale-free functional brain dynamics in non-hospitalized individuals.

Nathan W ChurchillEugenie RoudaiaJ Jean ChenAsaf GilboaAllison SekulerXiang JiFuqiang GaoZhongmin LinMario MasellisMaged GoubranJennifer S RabinBenjamin LamIvy ChengRobert FowlerChris HeynSandra E BlackBradley J MacIntoshSimon J GrahamTom A Schweizer

Published in: Brain and behavior (2023)

These findings provide new insights into the neurophysiological mechanisms that underlie persistent post-COVID headache, with reduced BOLD scaling as a potential biomarker that is specific to this debilitating condition.

Keyphrases

coronavirus disease
sars cov
resting state
functional connectivity
respiratory syndrome coronavirus
white matter
blood brain barrier
brain injury