A Detailed Analysis of the Association between Urate Deposition and Erosions and Osteophytes in Gout.

Caroline Pecherstorfer David SimonSara UnbehendHanna EllmannMatthias EnglbrechtFabian HartmannCamille FigueiredoAxel HueberJudith HaschkaRoland KocijanArnd Kleyer Larissa Valor-Méndez Juergen RechSara Bayat

Published in: ACR open rheumatology (2020)

Gout patients show increased changes in their bone microarchitecture. The extent of uric acid deposition is positively correlated with the extent of bone loss at the MTP1 joint, highlighting the strong cohesion of inflammation and erosive changes.

Keyphrases

uric acid
bone loss
metabolic syndrome
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
bone mineral density
patient reported outcomes
soft tissue