Disrupted BMP-9 Signaling Impairs Pulmonary Vascular Integrity in Hepatopulmonary Syndrome.

Fabien RobertMarie-Caroline CertainAudrey BaronRaphaël ThuilletLéa DuhautMina OttavianiMustapha Kamel ChelghamCorinne NormandNihel BerrebehNicolas RicardValerie FurlanAgnès Desroches-CastanEmmanuel GonzalesEmmanuel JacqueminOlivier SitbonMarc HumbertSabine BaillyAudrey CoillyChristophe GuignabertLy TuLaurent Savale

Published in: American journal of respiratory and critical care medicine (2024)

The study findings suggest that portal hypertension-induced loss of BMP-9 signaling contributes to HPS development.

Keyphrases

mesenchymal stem cells
blood pressure
pulmonary hypertension
high glucose
bone regeneration
case report
endothelial cells
drug induced
resting state
oxidative stress
bone marrow
stress induced