An in vitro investigation into the impact of corneal rinsing on riboflavin/UVA corneal cross-linking.
Siân R MorganDavid P S O'BrartJinhai HuangKeith M MeekSally HayesPublished in: Eye and vision (London, England) (2024)
All protocols, with and without rinsing, were effective at enhancing the resistance to collagenase digestion, although resistance was significantly decreased, and stromal riboflavin fluorescence reduced with a 10 mL rinse. This suggests that a 10 mL surface rinse can reduce the efficacy of CXL through the dilution of the stromal riboflavin concentration.