Aseptic meningitis in Fabry disease due to a novel GLA variant: an expanded phenotype?
Paulo Ribeiro NóbregaJoão Lucas Araújo MoraisAlliane Milliane FerreiraAlisson Dantas de MedeirosBeatrice Araújo DuarteDeborah Moreira RangelFabrício Oliveira LimaAnderson Rodrigues Brandão de PaivaLuciana Paim-MarquesFernando KokAndré Luiz Santos PessoaPedro Braga NetoFernanda Martins Maia CarvalhoPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)
We described aseptic meningitis in a family with a novel GLA variant. Meningitis might be a common phenomenon in FD and not a particularity of this variant. Understanding the mechanisms underlying meningitis and its association with cerebrovascular events may lead to a new paradigm of treatment for stroke in these patients. Further prospective studies with CSF collection in patients with FD and recurrent headache could help to elucidate this question.