Genetic Polymorphisms of GGH and ABCC2 Are Associated with Methotrexate Intolerance in Patients with Rheumatoid Arthritis.

Alejandro Escudero-Contreras Clementina López Medina Eduardo Collantes-EstevezRafaela Ortega-CastroJerusalem Calvo-GutiérrezNatalia Mena Vázquez Blanca Panero-LamotheBárbara Manzanares-MartínRafael Cáliz-CálizAlberto Jiménez-MoralesMayte Ruiz-JiménezPilar Font-Ugalde

Published in: Journal of clinical medicine (2021)

This study provides new data on the association between genetic polymorphisms and MTX intolerance, which may contribute to the development of new biomarkers and personalized medicine in patients with RA.

Keyphrases

rheumatoid arthritis
high dose
big data
disease activity
systemic sclerosis
data analysis