Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism.

Priyojit Das Rebeca San Martin Tian Hong Rachel Patton McCord

Published in: bioRxiv : the preprint server for biology (2024)

Computational analysis of a cohort of cancer cell lines reveals 3D genome spatial compartment changes are associated with transitions in cancer cell state that favor metastasis (EMT) and enable survival in a new organ context.

Keyphrases

epithelial mesenchymal transition
transforming growth factor
papillary thyroid
genome wide
signaling pathway
squamous cell
childhood cancer
squamous cell carcinoma
free survival