Copper-catalyzed transformation of alkyl nitriles to N -arylacetamide using diaryliodonium salts.

Romain SallioPierre-Adrien PayardPaweł Pakulski Iryna DiachenkoIndira FabreSabine Berteina-Raboin Cyril Colas Ilaria CiofiniLaurence GrimaudIsabelle Gillaizeau

Published in: RSC advances (2021)

This work reports a simple and efficient method for the copper-catalyzed redox-neutral transformation of alkyl nitriles using eco-friendly diaryliodonium salts and leading to N -arylacetamides. The method features high efficiency, broad substrate scope and good functional group tolerance.

Keyphrases

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