Copper-catalyzed transformation of alkyl nitriles to N -arylacetamide using diaryliodonium salts.
Romain SallioPierre-Adrien PayardPaweł PakulskiIryna DiachenkoIndira FabreSabine Berteina-RaboinCyril ColasIlaria CiofiniLaurence GrimaudIsabelle GillaizeauPublished in: RSC advances (2021)
This work reports a simple and efficient method for the copper-catalyzed redox-neutral transformation of alkyl nitriles using eco-friendly diaryliodonium salts and leading to N -arylacetamides. The method features high efficiency, broad substrate scope and good functional group tolerance.