Do patients with schizophreniform and bipolar disorders show an intrathecal, polyspecific, antiviral immune response? A pilot study.

Dominique EndresDaniela HuzlyRick DerschOliver StichBenjamin BergerFlorian SchuchardtEvgeniy PerlovNils VenhoffSabine HellwigBernd L FiebichDaniel ErnyTilman HottenrottLudger Tebartz van Elst

Published in: Fluids and barriers of the CNS (2017)

Our results indicate that the MRZR is highly specific to MS. Nevertheless, two schizodepressive patients also had a positive MRZR. This finding corresponds to the few MRZR-positive patients with OIND or other autoimmune disorders with central nervous involvement, implicating that the MRZR specificity for MS is high, but not 100%.

Keyphrases

multiple sclerosis
immune response
end stage renal disease
mass spectrometry
ms ms
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
bipolar disorder
patient reported outcomes
toll like receptor