Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative.

Ruth JohnsonYi DingVidhya VenkateswaranArjun BhattacharyaKristin BoulierAlec ChiuSergey KnyazevTommer SchwarzMalika FreundLingyu ZhanKathryn S BurchChrista CaggianoBrian HillNadav RakoczBrunilda BalliuChristopher T DennyJae Hoon SulNoah ZaitlenValerie A ArboledaEran HalperinSriram SankararamanManish J Buttenull nullClara LajonchereDaniel H GeschwindBogdan Pasaniuc

Published in: Genome medicine (2022)

Overall, our results explore the interplay between SIRE and GIA within a disease context and underscore the utility of studying the genomes of diverse individuals through biobank-scale genotyping linked with EHR-based phenotyping.

Keyphrases

electronic health record
high throughput
clinical decision support
single cell
adverse drug
small molecule
quality improvement
genome wide
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