Enhancing the Classification of Congenital Heart Defects for Outcome Association Studies in Birth Defects Registries.

Sara B Stephens Renata H Benjamin Keila N LopezBrett R AndersonAngela E LinCharlie J Shumate Wendy N Nembhard Shaine Alaine Morris A J Agopian

Published in: Birth defects research (2024)

This new CHD classification system for investigators using birth defect registry data, C-CLOC, is expected to balance clinical outcome homogeneity in analytic groups while maintaining sufficiently large case counts within categories, thus improving power for CHD-specific outcome association comparisons. Future outcome studies utilizing C-CLOC-based classifications are planned.

Keyphrases

machine learning
gestational age
case control
current status
pregnant women
big data
peripheral blood
resting state
data analysis