The effects of common structural variants on 3D chromatin structure.
Omar ShantaAmina Noornull nullJonathan SebatPublished in: BMC genomics (2020)
Our study demonstrates that common SVs in the population impact long-range chromatin structure, and deletions and inversions have distinct signatures. However, the effects that we observe are subtle and variable between loci. Genome-wide analysis of chromatin conformation in large cohorts will be needed to quantify the influence of common SVs on chromatin structure.