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Use of dupilumab for atopic dermatitis in young transplant patients-A case series of 3 patients.

Maritza V SteeleRachit GuptaSheilagh M MaguinessChristina Boull
Published in: Pediatric dermatology (2023)
Patients who undergo solid organ transplantation are at an increased risk of developing atopic dermatitis, potentially due to long-term use of calcineurin inhibitors which results in a shift towards the Th2 immune response. The effectiveness and safety of dupilumab for atopic dermatitis in posttransplant patients is not established. Previous reports of dupilumab use in posttransplant patients have been in adult patients. In this series, we report three young posttransplant patients treated successfully with dupilumab.
Keyphrases
  • atopic dermatitis
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • immune response
  • chronic kidney disease
  • prognostic factors
  • peritoneal dialysis
  • emergency department
  • mesenchymal stem cells