Assessment of serum macrophage migration inhibitory factor (MIF), adiponectin, and other adipokines as potential markers of proteinuria and renal dysfunction in lupus nephritis: a cross-sectional study.

Jorge Ivan Gamez-NavaValeria Diaz-RizoEdsaul Emilio Perez-GuerreroJose Francisco Muñoz-ValleAna Miriam Saldaña-CruzNicte Selene Fajardo-RobledoHeriberto Jacobo-CuevasCesar Arturo Nava-ValdiviaMiriam Fabiola Alcaraz-LopezXochitl TrujilloMiguel HuertaErnesto German Cardona-MuñozGonzalez-Lopez Laura

Published in: Biomarker research (2020)

High adiponectin combined with low MIF concentrations int+eract to explain the severity of proteinuria in renal SLE. These findings highlight the relevance of adiponectin, resistin and MIF as markers of LN.

Keyphrases

metabolic syndrome
insulin resistance
systemic lupus erythematosus
adipose tissue
physical activity
oxidative stress
risk factors
skeletal muscle
rheumatoid arthritis