Exendin-4-based imaging in insulinoma localization: Systematic review and meta-analysis.

Ravikumar ShahRobin GargMonil MajmundarNilendu PurandareGaurav MalhotraVirendra PatilSwati S Jadhav Anurag Ranjan LilaNalini ShahTushar R Bandgar

Published in: Clinical endocrinology (2021)

For insulinoma localization, exendin-4 PET/CT should be preferred over exendin-4 SPECT/CT because of higher sensitivity and specificity. FP uptakes in Brunner's gland, normal pancreas, and other β-cell pathologies and FN results in tail lesions, and malignant insulinomas are limitations. Higher specificity for insulinoma localization is particularly useful in patients with MEN-1 syndrome.

Keyphrases

pet ct
positron emission tomography
computed tomography
high resolution
single cell
cell therapy
stem cells
magnetic resonance
bone marrow