Rhythm of Fetoplacental 11β-Hydroxysteroid Dehydrogenase Type 2 - Fetal Protection From Morning Maternal Glucocorticoids.

Eva Kathrin LamadéFerdinand HendlmeierStefan A WudyStephanie H WittMarcella RietschelMichaela CoenenMaria GillesMichael Deuschle

Published in: The Journal of clinical endocrinology and metabolism (2021)

Our study indicates a time-specific alteration of fetoplacental 11β-HSD2 activity with peaking levels in the morning, demonstrating a mechanism of fetal protection from the morning maternal glucocorticoid surge.

Keyphrases

birth weight
pregnancy outcomes
heart rate
physical activity
body mass index