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Markers of gastrointestinal permeability and dysbiosis in premenopausal women with PCOS: a case-control study.

Shilpa LingaiahRiikka K ArffmanLaure Morin-PapunenJuha S TapanainenTerhi Piltonen
Published in: BMJ open (2021)
Intestinal permeability markers zonulin and FABP2, and the dysbiosis marker indican do not seem to be altered in women with PCOS at age 46 compared with BMI-matched controls. Serum zonulin levels correlated with BMI, insulin resistance and inflammatory marker levels, but did not segregate women with PCOS and controls. This suggests that metabolic factors, but not PCOS per se, is the driving force of dysbiosis in premenopausal women with PCOS.
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