Effect of HER2-targeted therapy on PDX and PDX-derived organoids generated from HER2-positive salivary duct carcinoma.

Jun AoyamaYusuke NojimaDaisuke SanoYuri HiraiNatsumi KijimaYoshihiro AizawaKentaro TakadaTakashi HatanoHideaki TakahashiGoshi NishimuraNobuhiko Oridate

Published in: Head & neck (2023)

For the first time, we demonstrated the efficacy of anti-HER2 therapy in HER2-positive SDC using preclinical models of SDC PDX and PDXO.

Keyphrases

stem cells
cell therapy