Epidermal growth factor receptor inhibition downregulates Helicobacter pylori-induced epithelial inflammatory responses, DNA damage and gastric carcinogenesis.
Johanna C SierraMohammad AsimThomas G VerriereM Blanca PiazueloGiovanni SuarezJudith Romero-GalloAlberto G DelgadoLydia E WroblewskiDaniel P BarryRichard M PeekAlain P GobertKeith T WilsonPublished in: Gut (2017)
These findings suggest that epithelial EGFR inhibition represents a potential strategy to prevent development of gastric carcinoma in H. pylori-infected individuals.