Immune responses to SARS-CoV-2 vaccination in multiple sclerosis: a systematic review/meta-analysis.

Grace Y GombolayMonideep DuttWilliam Tyor

Published in: Annals of clinical and translational neurology (2022)

Antibody responses are decreased in S1PM and anti-CD20; however, cellular responses were positive in most anti-CD20 with decreased T cell responses in S1PM. mRNA vaccines had increased seroconversion rates compared to non-RNA vaccines. Further investigation in how DMTs affect vaccine immunity are needed.

Keyphrases

sars cov
multiple sclerosis
systematic review
immune response
particulate matter
air pollution
heavy metals
polycyclic aromatic hydrocarbons
nk cells
meta analyses
respiratory syndrome coronavirus
toll like receptor
water soluble
inflammatory response
risk assessment