Targeted proteomic profiling of cardiogenic shock in the cardiac intensive care unit.
Siddharth M PatelMathew S LopesDavid A MorrowAndrea BellaviaAnkeet S BhattKayleigh K ButlerJessica D'AntonioMichael DunnAntonio A FagundesPetr JarolímEthan P MarinLori MortonBenjamin O OlenchockBalimkiz SenmanDanuzia S da SilvaAnubodh S VarshneyErin A BohulaDavid D BergPublished in: European heart journal. Acute cardiovascular care (2024)
In this pilot study of targeted proteomic profiling in CS, we identified nine biomarkers significantly associated with CS when cross-validated against non-shock controls including those with HF or isolated hypotension, illustrating the potential application of a targeted proteomic approach to identify novel candidates that may support the diagnosis of CS.