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Increased urinary markers of kidney damage in the institutionalized frail elderly due to recurrent urinary tract infections.

María-Fernanda Lorenzo-GómezMaría-Carmen Flores-FraileMagaly-Teresa Márquez-SánchezJavier Flores FraileIgnacio González-CasadoBárbara Padilla-FernándezSebastián Valverde-MartínezTeresa Hernández SánchezCarlos Muller-ArteagaMaría-Begoña García-Cenador
Published in: Therapeutic advances in urology (2020)
Frail elderly with RUTI have higher urinary levels of renal injury markers, specifically NGAL, NAG, and TGFβ-1, chronically in periods between urinary tract infection (UTI). Urinary markers of renal injury, specifically NGAL, NAG, and TGFβ-1, identify early deterioration of renal function, compared with serum creatinine, or albuminuria, in frail elderly with recurrent urinary infections.
Keyphrases
  • urinary tract infection
  • community dwelling
  • middle aged
  • transforming growth factor
  • oxidative stress
  • metabolic syndrome
  • epithelial mesenchymal transition
  • uric acid