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Green Synthesis and Antibacterial Activity of Ag/Fe 2 O 3 Nanocomposite Using Buddleja lindleyana Extract.

Fatimah A M Al-ZahraniSalem S SalemHuda A Al-GhamdiLaila M NhariLong LinReda M El-Shishtawy
Published in: Bioengineering (Basel, Switzerland) (2022)
In the study reported in this manuscript, silver/iron oxide nanocomposites (Ag/Fe 2 O 3 ) were phytosynthesized using the extract of Buddleja lindleyana via a green, economical and eco-friendly strategy. The biosynthesized Ag/Fe 2 O 3 nanocomposites were characterized using UV-Vis spectrophotometry, FTIR, XRD, TEM, DLS and SEM-EDX analyses. The particulates showed a triangular and spherical morphology having sizes between 25 and 174 nm. FTIR studies on the nanoparticles showed functional groups corresponding to organic metabolites, which reduce and stabilize the Ag/Fe 2 O 3 nanocomposite. The antimicrobial efficacy of the phytosynthesized Ag/Fe 2 O 3 against bacterial pathogens was assessed. In addition, Ag/Fe 2 O 3 exhibited broad spectrum activities against B. subtilis , S. aureus , E. coli , and P. aeruginosa with inhibition zones of 23.4 ± 0.75, 22.3 ± 0.57, 20.8 ± 1.6, and 19.5 ± 0.5 mm, respectively. The Ag/Fe 2 O 3 composites obtained showed promising antibacterial action against human bacterial pathogens ( S. aureus , E. coli , B. subtilis and P. aeruginosa ), making them candidates for medical applications.
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