Post-explant profiling of subcellular-scale carbon fiber intracortical electrodes and surrounding neurons enables modeling of recorded electrophysiology.
Joseph G LetnerParas R PatelJung-Chien HsiehIsrael M Smith FloresElena Della ValleLogan A WalkerJames D WeilandCynthia A ChestekDawen CaiPublished in: Journal of neural engineering (2023)
Collectively, these data and simulations provide the first direct evidence that neuron placement in the immediate vicinity of the recording site influences how many spike clusters can be reliably identified by spike sorting.