Weak base-promoted selective rearrangement of oxaziridines to amides via visible-light photoredox catalysis.
Jin ParkSehoon ParkGwang Seok JangRan Hui KimJaehoon JungSang Kook WooPublished in: Chemical communications (Cambridge, England) (2021)
The selective rearrangement of oxaziridines to amides via a single electron transfer (SET) pathway is unexplored. In this study, we present a weak base-promoted selective rearrangement of oxaziridines to amides via visible-light photoredox catalysis. The developed method shows excellent functional group tolerance with a broad substrate scope and good to excellent yields. Furthermore, control experiments and density functional theory (DFT) calculations are performed to gain insight into the reactivity and selectivity.