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Chemokine receptor antagonists with α1-adrenergic receptor blocker activity.

Anthony J DeSantisGarrett A EntenXianlong GaoMatthias Majetschak
Published in: Journal of basic and clinical physiology and pharmacology (2021)
Our data suggest that CCR antagonists should be screened for cross-reactivity with α1-adrenoceptors to exclude potential adverse cardiovascular effects when used as anti inflammatory drugs.
Keyphrases
  • anti inflammatory drugs
  • electronic health record
  • big data
  • regulatory t cells
  • human health
  • angiotensin converting enzyme
  • deep learning