Investigation of circRNA Expression Profiles and Analysis of circRNA-miRNA-mRNA Networks in an Animal (Mouse) Model of Age-Related Macular Degeneration.
Xiao LiuLiwei ZhangJiang-Hui WangHuilan ZengJingling ZouWei TanHan ZhaoYan HeJingming ShiShigeo YoshidaYunping LiYedi ZhouPublished in: Current eye research (2020)
The study identified statistically significant differences between CNV-mouse circRNAs and control mouse circRNAs, suggesting that circRNAs play vital roles in the pathogenesis of CNV. It is, therefore, reasonable to consider circRNAs as potential therapeutic targets for regulating CNV in AMD patients.