In vivo effect of LATE-NC on integrity of white matter connections to the hippocampus.
Ashley HeywoodJane StocksJulie A SchneiderKonstantinos ArfanakisDavid A BennettMirza Faisal BegLei WangPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Post mortem TDP-43 pathological burden is associated with reduced ante mortem fractional anisotropy. Reduced FA located in the parahippocampal portion of the cingulum. FA in this area was associated with reduced episodic and semantic memory. FA in this area was associated with increased inward hippocampal surface deformation.