Incidental Finding of an Asymptomatic Jejunal Schwannoma: A Rare Case Report and Review of Literature.
Konstantina KatsiafliakaEleni KarlaftiGeorgios TzikosPatroklos GoulasApostolos ZatagiasAngeliki VoucharaElisavet PsomaAnastasia TsakonaGeorgios PetrakisDaniel ParamythiotisPublished in: The American journal of case reports (2024)
BACKGROUND Schwannomas are tumors that arise from Schwann cells that surround and support nerve cells. Most common sites for presentations are head, neck, and extremities. Schwannomas of gastrointestinal tract are rare, slow-growing tumors, usually benign, arising from gastrointestinal tract's neural plexus. They are histologically distinguishable from conventional schwannomas that arise in soft tissue or the central nervous system. Preoperative diagnosis of gastrointestinal schwannoma is challenging, requiring immunohistological confirmation of the nature of the tumor. Here, we report a case of 57-year-old woman with an incidental finding of an asymptomatic submucosal jejunal schwannoma. CASE REPORT A 57-year-old woman with a medical history of hematological disorder underwent a contrast abdominal computed tomography as part of medical follow-up. The imaging revealed the presence of a jejunal mass. The patient underwent laparoscopic surgical resection of the lesion, followed by side-to-side jejuno-jejunal anastomosis with 4-cm clear surgical margins. The final pathologic study revealed the presence of jejunal schwannoma, as tested positive for S-100 protein. The patient was discharged home on the fourth postoperative day, having an uneventful recovery. CONCLUSIONS Jejunal schwannoma are usually benign and asymptomatic, and they are often discovered incidentally during diagnostic tests for other conditions; therefore, it should be included in the differential diagnosis of gastrointestinal tumors. Surgical treatment appears to be necessary to achieve a definitive diagnosis through a biopsy of the tumor tissue. Benign jejunal schwannomas have a good prognosis.
Keyphrases
- case report
- induced apoptosis
- computed tomography
- healthcare
- soft tissue
- cell cycle arrest
- patients undergoing
- magnetic resonance imaging
- high resolution
- single cell
- positron emission tomography
- squamous cell carcinoma
- locally advanced
- oxidative stress
- ultrasound guided
- cell proliferation
- signaling pathway
- radiation therapy
- peripheral nerve
- contrast enhanced
- endoplasmic reticulum stress
- pi k akt
- neoadjuvant chemotherapy
- amino acid
- small molecule
- photodynamic therapy
- binding protein