Trial Sequential Analysis in systematic reviews with meta-analysis.

Jorn WetterslevJanus Christian JakobsenChristian Gluud

Published in: BMC medical research methodology (2017)

Trial Sequential Analysis represents analysis of meta-analytic data, with transparent assumptions, and better control of type I and type II errors than the traditional meta-analysis using naïve unadjusted confidence intervals.

Keyphrases

systematic review
clinical trial
study protocol
meta analyses
phase iii
phase ii
emergency department
electronic health record
machine learning
open label
artificial intelligence
adverse drug
double blind
case control