Phenotypic Differences Among Familial Partial Lipodystrophy Due to LMNA or PPARG Variants.

Compared with subjects with FPLD2, subjects with FPLD3 have milder lipodystrophy but develop more severe metabolic complications, suggesting that the remaining adipose tissue in subjects with FPLD3 may be dysfunctional or those with mild metabolic disease are underrecognized.