Metabolic alterations in meningioma reflect the clinical course.
Waseem MasalhaKaram DakaJakob WoernerNils PompeStefan WeberDaniel DelevMarie T KrügerOliver SchnellJürgen BeckDieter Henrik HeilandJuergen GrauvogelPublished in: BMC cancer (2021)
Our findings suggest that alterations in glycine/serine metabolism are associated with lower proliferation and more recurrent tumours. Altered choline/tryptophan metabolism was associated with increases proliferation, and recurrence. Our results suggest that tumour malignancy can be reflected by metabolic alterations, which may support histological classifications to predict the clinical outcome of patients with meningiomas.
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