Contribution of the inflammasome to inflammaging.

Nancy H MejiasCamila C MartinezMarisa E StephensJuan Pablo de Rivero Vaccari

Published in: Journal of inflammation (London, England) (2018)

Taken together, our data indicate that the inflammasome contributes to inflammaging and that the inflammasome-mediated cell death mechanism of pyroptosis contributes to cell demise in the aging brain.

Keyphrases

cell death
single cell
cell therapy
white matter
nlrp inflammasome
multiple sclerosis
mesenchymal stem cells
data analysis