Ommaya reservoir use in pediatric ALL and NHL: a review at St. Jude Children's Research Hospital.
Alyssa GaiettoJohn C PanettaJennifer L PauleyMary V RellingRaul RibeiroMatthew J EhrhardtChing-Hon PuiHiroto InabaHope D SwansonPublished in: Cancer chemotherapy and pharmacology (2024)
OmR were able to be safely placed and administer intraventricular methotrexate with and without boost doses in patients from 7 days to 22 years old. Boosting strategies are predicted to increase CSF methotrexate concentrations ≥ 1 µM for 72 h.