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The effect of herpes simplex virus vector-mediated gene therapy of protein phosphatase 1α on bladder overactivity and nociception.

Tsuyoshi MajimaKenichi MoriKatsumi KadekawaShun TakaiYasuhito FunahashiBonnie ReinhartWilliam F GoinsMomokazu GotohJoseph C GloriosoEi-Ichiro Takaoka
Published in: Neurourology and urodynamics (2018)
HSV vectors-mediated PP1α gene therapy may be an alternative treatment modality for cystitis-related hypersensitive bladder condition at least in part via modulation of the IP3 R signaling pathway.
Keyphrases
  • gene therapy
  • herpes simplex virus
  • signaling pathway
  • spinal cord injury
  • urinary tract
  • pi k akt
  • epithelial mesenchymal transition
  • oxidative stress
  • cell proliferation
  • botulinum toxin
  • drug induced